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Neural DSP Nano Cortex settings

Mr. Brightside settings for Neural DSP Nano Cortex

The Killers · adapted 4 times on ToneAdapt

To get the The Killers "Mr. Brightside" riff tone on a Neural DSP Nano Cortex, use the US HRDLX ChA 6 amp model on the crunch channel, then set Drive 5, Master 7, Bass 4, Mid 7, Treble 8, Presence 6. Use the bridge pickup with your guitar's tone on 8 and volume on 8-9.

Riff settings

updated 2026-11-14

Amp model
US HRDLX ChA 6
Channel
Crunch
Cab
Open Back
Pickup
Bridge pickup
Guitar knobs
Tone 8 · Volume 8-9

Amp block

Drive
5
Master
7
Bass
4
Mid
7
Treble
8
Presence
6
Original drive
5

Effects chain

  1. 1overdriveChief OD1Gain 5 · Tone 6 · Level 7
  2. 2modulationChorus 229TMix 5 · Rate 5 · Depth 5
  3. 3reverbRoomMix 6 · Decay 5

Playing tips

  • Focus on a clean attack to maintain clarity in the riff.
  • Use a light palm muting technique to add definition to the notes.
  • Experiment with a slow chorus effect to replicate the ambient depth of the original tone.

The original rig

What The Killers used on the recording, for reference. ToneAdapt translates this to the controls your Neural DSP Nano Cortex actually has.

Guitar
Fender Stratocaster (likely American Standard, early 2000s, as used by Dave Keuning on the studio recording)
Amp
Fender Hot Rod DeVille (studio recording, 2003 era; Fender-style amp confirmed by multiple sources)
Gain
4.5
Bass
4.5
Mid
7
Treble
8
Presence
6
Reverb
5
Full Mr. Brightside tone breakdown, effects and sources →

Different guitar or pedals? Get Mr. Brightside adapted to your exact rig

These settings were generated for the gear named above. ToneAdapt adapts The Killers's tone to your own guitar, pickups, amp and pedals in seconds.

Frequently asked questions

What amp model should I use on the Neural DSP Nano Cortex for Mr. Brightside?

Use the US HRDLX ChA 6 (crunch channel) with Drive 5, Master 7, Bass 4, Mid 7, Treble 8, Presence 6, followed by Chief OD1, Chorus 229T, Room.

Which pickup should I use for Mr. Brightside?

Bridge pickup, with the guitar's tone at 8 and volume at 8-9.

What gear did The Killers use on Mr. Brightside?

Guitar: Fender Stratocaster (likely American Standard, early 2000s, as used by Dave Keuning on the studio recording). Amp: Fender Hot Rod DeVille (studio recording, 2003 era; Fender-style amp confirmed by multiple sources).

Will these settings work with my guitar?

Different pickups change how much gain and treble you need. ToneAdapt adapts the tone to your exact guitar, pickups, amp and pedals.

Popular songs on the Neural DSP Nano Cortex

All 25 songs for the Neural DSP Nano Cortex →

Settings are generated by ToneAdapt's tone adaptation for the gear named on this page and are a starting point — every amp, guitar and room is a little different.