| Reptilia · riff | Riff · distorted | Fender Stratocaster (Albert Hammond Jr.) | Fender Hot Rod DeVille 2x12 | 5 |
| You Only Live Once · riff | Riff · distorted | Epiphone Riviera (early 2000s, stock mini-humbuckers, natural finish) | Fender Hot Rod DeVille 212 (60W 2x12 combo, silverface, early 2000s) | 5.5 |
| Is This It · riff | Riff · distorted | Epiphone Casino (Albert Hammond Jr.) | Fender Hot Rod DeVille 2x12 | 4.5 |
| Someday · riff | Riff · distorted | Epiphone Riviera (stock, with Gibson P-94 pickups) | Fender Hot Rod DeVille 212 | 5.5 |
| Hard to Explain · riff | Riff · distorted | Epiphone Riviera (1995, modified with Gibson P-94 pickups) | Fender Hot Rod DeVille 2x12 | 5 |
| Last Nite · solo | Solo · distorted | Epiphone Riviera (stock, semi-hollow, stop tailpiece, chrome P-94 pickups) | Fender Hot Rod Deville 2x12 | 5.5 |
| Reptilia · solo | Solo · distorted | Epiphone Riviera with Gibson P-94 pickups | Fender Hot Rod DeVille 2x12 | 5 |
| Selfless · riff | Riff · distorted | Epiphone Riviera (likely 1990s Korean model, as used by Nick Valensi on The New Abnormal sessions) | Fender Hot Rod DeVille 212 (studio recording, as used by Nick Valensi on The New Abnormal era) | 5 |
| At The Door · riff | Riff · clean | Fender Stratocaster (likely Albert Hammond Jr's signature or vintage model) | Fender Hot Rod DeVille 2x12 | 0 |
| Oblivius · solo | Solo · distorted | Epiphone Riviera P94 (Nick Valensi signature, semi-hollow, P-94 pickups) | Fender Hot Rod DeVille 212 | 6.5 |
| Selfless · solo | Solo · distorted | Epiphone Elitist Riviera (Nick Valensi signature, semi-hollow, 2000s-2020s version) | Vox AC30 Custom Classic (likely CC2 or CC2X, studio version) | 5.5 |
| The Adults Are Talking · riff | Riff · distorted | Fender Stratocaster | Fender Hot Rod DeVille 212 III | 3.5 |
| You Only Live Once · solo | Solo · distorted | 1985 Fender Stratocaster (Japanese '72 reissue, Olympic White) | Fender Hot Rod DeVille 2x12 | 4.5 |
| 50/50 · riff | Riff · distorted | Epiphone Riviera | Fender Hot Rod DeVille 212 | 7 |
| Alone, Together · solo | Solo · distorted | Epiphone Riviera | Fender Hot Rod DeVille 2x12 | 6 |
| Alone, Together · riff | Riff · distorted | Fender Stratocaster (likely 1970s reissue, single coil pickups, as used by Albert Hammond Jr. on 'Is This It') | Fender Hot Rod DeVille 212 (used by The Strokes on 'Is This It' album, including 'Alone, Together') | 5.5 |
| Automatic Stop · riff | Riff · distorted | Fender Stratocaster (Albert Hammond Jr.) | Fender Hot Rod DeVille 212 | 4 |
| Automatic Stop · solo | Solo · distorted | Epiphone Riviera | Fender Hot Rod DeVille 2x12 | 3.5 |
| Call It Fate, Call It Karma · riff | Riff · clean | Epiphone Riviera (likely vintage, semi-hollow, as used by Nick Valensi in this era) | Fender Hot Rod DeVille (4x10, as used by Nick Valensi in studio and live in this era) | 0 |
| Dine N'Dash · riff | Riff · distorted | Fender Stratocaster Artist Series Albert Hammond Jr. | Fender '68 Custom Princeton Reverb (studio capture via Tonex) | 5 |
| Eternal Summer · riff | Riff · distorted | Epiphone Riviera | Fender Hot Rod DeVille 212 | 5.5 |
| Going Shopping · riff | Riff · distorted | Fender Stratocaster (likely Japanese or American, as used by Nick Valensi on studio recordings) | Fender Twin Reverb (studio recording standard for The Strokes, especially for clean/edge-of-breakup tones) | 5 |
| Going to Babble On · riff | Riff · distorted | Epiphone Riviera | Fender Hot Rod DeVille 212 | 5 |
| Hard to Explain · riff | Riff · clean | Fender American Professional II Stratocaster | Fender Hot Rod Deluxe IV | 0 |
| Is This It · riff | Riff · clean | Epiphone Riviera (early 2000s, stock mini-humbuckers, used by Nick Valensi on studio recording) | Fender Hot Rod DeVille 2x12 combo | 3 |
| Juicebox · riff | Riff · distorted | Epiphone Elitist Riviera | Fender Hot Rod DeVille 212 | 7 |
| Last Nite · riff | Riff · distorted | Epiphone Riviera (stock, semi-hollow, stop tailpiece, chrome P-94 pickups) | Fender Hot Rod Deville 2x12 combo | 3.5 |
| Life Is Simple In the Moonlight · riff | Riff · distorted | Fender Jazzmaster (likely 1960s reissue, as used by Nick Valensi/Albert Hammond Jr. on Angles era) | Fender Hot Rod DeVille 212 | 3.5 |
| Life Is Simple In the Moonlight · solo | Solo · distorted | Epiphone Riviera (early 2000s, semi-hollow, used by Nick Valensi) | Fender Hot Rod DeVille 212 (studio recording amp for Nick Valensi on Angles era) | 4.5 |
| New York City Cops (Live In Iceland) · riff | Riff · distorted | Fender Stratocaster 1985 Re-Issue | Fender Hot Rod DeVille 212 III 60W 2x12 Tube Guitar Combo Amp | 6 |
| Oblivius · riff | Riff · distorted | Epiphone Nick Valensi Riviera P-94 | Fender Hot Rod Deville | 6.5 |
| Razorblade · riff | Riff · distorted | Epiphone Riviera (1990s Korean, stock mini-humbuckers replaced with Gibson P-94 single-coil-sized P-90s) | Fender Hot Rod DeVille 212 (original USA model, studio recording) | 5.5 |
| Red Light · riff | Riff · distorted | Epiphone Riviera (early 2000s, semi-hollow, stock mini-humbuckers, Nick Valensi's main studio guitar) | Vox AC30 (early 2000s reissue, likely Top Boost channel, studio recording) | 6 |
| Reptilia · solo | Solo · clean | Epiphone Riviera (early 2000s, semi-hollow, used by Nick Valensi on studio recording) | Fender Hot Rod DeVille 2x12" combo | 0 |
| Reptilia · distorted | Distorted · distorted | Fender Precision Bass | Ampeg SVT Classic (likely vintage, studio use) | 6 |
| Reptilia · riff | Riff · clean | Epiphone Riviera | Fender Hot Rod DeVille 212 (studio; likely clean channel) | 0 |
| Selfless · riff | Riff · clean | Epiphone Riviera (Nick Valensi's main guitar, likely used for clean riff sections on 'Selfless') | Fender Twin Reverb (most cited clean amp for The Strokes, especially for Nick Valensi's clean tones in studio) | 0 |
| Soma · riff | Riff · distorted | Fender Stratocaster (Albert Hammond Jr.'s main guitar on 'Is This It') | Fender Hot Rod DeVille (studio amp for 'Is This It') | 5.5 |
| Soma · riff | Riff · clean | Fender Stratocaster (likely 1970s reissue, Albert Hammond Jr.) | Fender Hot Rod DeVille 2x12 | 3.5 |
| Someday · solo | Solo · distorted | Epiphone Riviera (stock, likely 1990s Korean model) | Fender Hot Rod DeVille 212 (original USA model, early 2000s) | 5.5 |
| Someday · riff | Riff · clean | Epiphone Casino | Fender Hot Rod DeVille 212 | 0 |
| Take It or Leave It · riff | Riff · distorted | Epiphone Casino (Julian Casablancas) or Fender Stratocaster (Nick Valensi), likely Epiphone Casino for riff | Fender Hot Rod DeVille 212 or Hot Rod Deluxe | 6 |
| Taken For a Fool · solo | Solo · distorted | Epiphone Riviera (early 2000s, semi-hollow, stock pickups) | Fender Hot Rod DeVille 212 (studio recording era typical for Nick Valensi) | 5.5 |
| Tap Out · riff | Riff · distorted | Epiphone Elitist Riviera (Nick Valensi signature, semi-hollow, likely used for studio recording on 'Tap Out') | Fender Hot Rod DeVille (studio, as per band interviews and forum consensus for Comedown Machine era) | 5 |
| The Adults Are Talking · riff | Riff · clean | Fender Stratocaster | Roland JC-120 Jazz Chorus | 0 |
| The End Has No End · riff | Riff · distorted | Epiphone Riviera | Fender Hot Rod DeVille 212 | 3.5 |
| The Modern Age · solo | Solo · distorted | 1995 Epiphone Riviera (hot-rodded with Gibson P-94 pickups) | Fender Hot Rod DeVille 2x12 | 6.5 |
| The Modern Age · riff | Riff · distorted | Fender Stratocaster (Albert Hammond Jr.) | Fender Hot Rod DeVille 2x12 | 6 |
| The Way It Is · riff | Riff · distorted | Epiphone Riviera (Nick Valensi, main riff guitar on 'Is This It' era) | Fender Hot Rod DeVille 212 | 6 |
| Trying Your Luck · riff | Riff · distorted | Epiphone Riviera (Nick Valensi's main guitar on Is This It) | Unknown studio amp (not Fender Hot Rod DeVille); possibly a vintage Fender or Vox, but not confirmed for this track | 5 |
| Under Control · distorted | Distorted · distorted | Fender Precision Bass | Ampeg SVT (likely SVT Classic or SVT-VR) | 5.5 |
| Under Control · riff | Riff · clean | Fender Stratocaster '70s Reissue (Albert Hammond Jr.) | Fender Hot Rod DeVille 2x12 | 2.5 |
| Under Control · clean | Clean · clean | Fender Precision Bass | Ampeg SVT Classic | 0 |
| Under Cover of Darkness · riff | Riff · clean | Epiphone Riviera | Fender Hot Rod DeVille 2x12 | 0 |
| Under Cover of Darkness · solo | Solo · distorted | Epiphone Riviera (sunburst, semi-hollow, as used by Nick Valensi on studio recording and in live performances of 'Under Cover of Darkness') | Fender Hot Rod DeVille 2x12 | 6 |
| Under Cover of Darkness · riff | Riff · distorted | Fender Stratocaster (Albert Hammond Jr.) | Fender Hot Rod DeVille 212 | 5 |
| Welcome To Japan · riff | Riff · distorted | Fender Stratocaster (likely 1960s or reissue, as used by Nick Valensi and Albert Hammond Jr. in studio) | Fender Hot Rod DeVille (studio standard for The Strokes, no evidence of Marshall or Vox on this track) | 4.5 |
| What Ever Happened? · riff | Riff · distorted | Fender American Vintage '52 Telecaster (AVRI Reissue) | Fender Hot Rod DeVille 212 | 5 |
| Why Are Sundays So Depressing · riff | Riff · distorted | Epiphone Riviera | Fender Hot Rod DeVille (likely, based on era and The Strokes' studio rig) | 5 |
| Why Are Sundays So Depressing · riff | Riff · clean | Fender Stratocaster (likely 1960s or reissue, as used by Nick Valensi for clean tones on The New Abnormal) | Fender Hot Rod DeVille (studio, as per The Strokes' typical clean amp for Nick Valensi in this era) | 0 |
| You Only Live Once · riff | Riff · clean | Fender Stratocaster (Albert Hammond Jr.) | Fender Hot Rod Deville 2x12 combo | 3.5 |