| Plug in Baby · riff | Riff · distorted | Manson MB-1 | Marshall JCM 2000 DSL 100 | 7.5 |
| Supermassive Black Hole · riff | Riff · distorted | Manson MB-1 (custom, built by Hugh Manson for Matt Bellamy) | Diezel VH4 (studio recording, 2006 era) | 7.5 |
| Hysteria · riff | Riff · distorted | Gibson SG Standard (red, used by Matt Bellamy on Absolution recording) | Unknown exact model (no direct source for amp used on 'Hysteria' studio recording; likely Marshall or similar British high-gain amp typical for Muse in this era, but not confirmed in sources) | 7.5 |
| Knights of Cydonia · riff | Riff · distorted | Manson MB-1 | Diezel VH4 | 7.5 |
| Cryogen · riff | Riff · distorted | Manson MB-1 | Diezel VH4 | 8.5 |
| Hysteria · distorted | Distorted · distorted | Pedulla Rapture RB5 (presumed studio/live use) | Marshall DBS 7400 (three amps: one clean, two distorted) | 8.5 |
| Be With You · solo | Solo · distorted | Gibson Les Paul Doublecut Lite | Diezel VH4 (studio blend with Vox AC30 possible, but Diezel VH4 primary for high-gain solo) | 7.5 |
| New Born · riff | Riff · distorted | Manson Delorean (custom-built by Hugh Manson for Matt Bellamy) | Marshall DSL100 (Dual Super Lead 100W head, likely with Marshall 1960A 4x12 cabinet) | 8.5 |
| Stockholm Syndrome · riff | Riff · distorted | Manson MB-1 | Diezel VH4 | 8.5 |
| Can't Take My Eyes Off You · riff | Riff · distorted | Manson MB-1 | Diezel VH4 | 7.5 |
| MK Ultra · riff | Riff · distorted | Manson MB-1 | Diezel VH4 | 8 |
| Time is Running Out · riff | Riff · distorted | Manson MB-1 | Diezel VH4 | 7 |
| Assassin · riff | Riff · distorted | Manson MB-1 | Diezel VH4 | 8.5 |
| Can't Take My Eyes Off You · riff | Riff · clean | Manson MB-1 | Vox AC30 (likely, based on era and typical Muse clean tones) | 0 |
| Darkshines · riff | Riff · distorted | Manson MB-1 (custom, early 2000s version) | Line 6 POD 2.0 (amp modeling direct to desk, no traditional amp on studio recording) | 7.5 |
| Hyper Music · riff | Riff · distorted | Gibson Les Paul DC Lite | Soldano Decatone (studio high-gain), Marshall JCM2000 DSL100 (studio low-drive) | 8.5 |
| Hysteria · clean | Clean · clean | Pedulla Rapture RB5 | Marshall DBS 7400 (with 8×10 cabinet) and Ampeg SVT (recorded via Neumann U47 FET mic) | 0 |
| Resistance · riff | Riff · distorted | Manson MB-1 | Diezel VH4 (studio), blended with Marshall Plexi Reissue and Vox AC30 | 7 |
| Sunburn · riff | Riff · distorted | Yamaha Pacifica 120SD (modified with DiMarzio pickups, Roland GK2 pickup) | Marshall JCM2000 DSL100 | 7.5 |
| Animals · riff | Riff · clean | Manson MB-1 | Diezel VH4 | 0 |
| Animals · riff | Riff · distorted | Manson MB-1 | Diezel VH4 | 6 |
| Animals · solo | Solo · distorted | Manson MB-1 | Diezel VH4 (studio blend, likely with Marshall and/or Vox AC30) | 7 |
| Ashamed · riff | Riff · distorted | Manson MB-1 | Marshall DSL100 | 8 |
| Be With You · riff | Riff · distorted | Manson MB-1 | Diezel VH4 | 7.5 |
| Bliss · riff | Riff · distorted | Manson MB-1 | Marshall JCM800 (modified by Matt Wells) | 7.5 |
| Bliss · solo | Solo · distorted | Manson MB-1 | Marshall 1959HW Handwired Plexi Head | 7.5 |
| Bliss · distorted | Distorted · distorted | Unknown | Unknown | 6.5 |
| Cave · riff | Riff · distorted | Manson MB-1 (early prototype, Showbiz era, likely with Seymour Duncan JB bridge pickup) | Marshall Plexi (likely 1959SLP, or similar Plexi model, as referenced for Showbiz era and tone discussions) | 6.5 |
| Citizen Erased · riff | Riff · distorted | Manson MB-1 (custom, 6-string, tuned low E to A) | Marshall DSL100 (likely, based on era and Muse's studio use) | 8 |
| Coma · riff | Riff · distorted | Manson MB-1 | Marshall DSL100 | 8 |
| Cryogen · riff | Riff · clean | Manson MB-1 | Unknown (not specified for this song/section; likely a Marshall or Diezel based on Muse's studio history, but no direct source for 'Cryogen' clean section) | 0 |
| Cryogen · distorted | Distorted · distorted | Status Graphite S2-Classic (custom, Chris Wolstenholme signature) | Ampeg SVT-4 PRO with Ampeg 8x10 cabinet (studio context inferred from Muse's standard setup) | 7 |
| Cryogen · solo | Solo · distorted | Manson MB-1 | Marshall JVM410H | 7.5 |
| Dead Inside · riff | Riff · distorted | Manson MB-1 | Vox AC30 (likely blended with Marshall, but AC30 primary for Drones era studio) | 7.5 |
| Dead Star · riff | Riff · distorted | Manson MB-1 | Diezel VH4 | 8 |
| Eternally Missed · solo | Solo · distorted | Fender Stratocaster | Unknown (likely Marshall or Diezel based on Muse's 2000s studio use, but not confirmed for this track) | 8 |
| Euphoria · riff | Riff · distorted | Manson MB-1 | Diezel VH4 | 7 |
| Euphoria · solo | Solo · distorted | Manson MB-1 | Diezel VH4 | 7 |
| Exo-Politics · solo | Solo · distorted | Manson MB-1 | Diezel VH4 | 7.5 |
| Feeling Good · solo | Solo · distorted | Manson MB-1 | Diezel VH4 | 8 |
| Fillip · riff | Riff · distorted | Gibson Les Paul DC Lite (modified with Roland GK2 pickup, likely DiMarzio humbuckers) | Marshall JCM2000 DSL100 | 7 |
| Fury · riff | Riff · distorted | Manson MB-1 (custom, early 2000s, likely with built-in Fuzz Factory and sustainer, as used by Matt Bellamy on Absolution-era recordings) | Diezel VH4 (studio, Absolution era, channel 3 high-gain) | 8 |
| Guiding Light · solo | Solo · distorted | Manson Works Floyd Rose Fuzz Factory Xenokroma | Diezel VH4 | 7 |
| Guiding Light · distorted | Distorted · distorted | Status Graphite S2-Classic (custom, headless, active electronics, used by Chris Wolstenholme on The Resistance era) | Ampeg SVT-4 PRO with Ampeg 8x10 cabinet (studio standard for Muse, confirmed for The Resistance era) | 6 |
| Hexagons · riff | Riff · distorted | Manson MB-1 (likely, based on era and Matt Bellamy's typical studio guitar for this period) | Diezel VH4 (likely, based on Muse's studio amp choices for modern riff tones) | 7.5 |
| Hexagons · solo | Solo · distorted | Gibson Les Paul DC Lite | Marshall 1959HW Handwired Plexi Head | 7 |
| Hysteria · solo | Solo · distorted | Manson MB-1 (custom, likely with Sustainiac and Bare Knuckle Nailbomb bridge humbucker) | Marshall 1959HW Handwired Plexi Head | 7.5 |
| Interlude · riff | Riff · distorted | Manson MB-1 | Diezel VH4 (Channel 3 – Heavy/Rock Channel) | 7.5 |
| Interlude · solo | Solo · clean | Manson MB-1 | Kemper Profiling Amp (profiled from Diezel VH4 or Marshall DSL, likely studio profile) | 0 |
| Kill Or Be Killed · solo | Solo · distorted | Manson Oryx (custom multi-scale, 6-string, Drop B tuning) | Orange Dual Terror DT30H 30W Tube Guitar Amp Head | 8.5 |
| Kill Or Be Killed · riff | Riff · distorted | Manson Oryx 6-string (custom, drop B tuning) | Diezel VH4 | 8.5 |
| Knights of Cydonia · solo | Solo · distorted | Manson MB-1 | Diezel VH4 | 7.5 |
| Knights of Cydonia · riff | Riff · clean | Manson Chrome Bomber Electric Guitar | Marshall JCM800 (modded by Matt Wells) | 0 |
| Knights of Cydonia · distorted | Distorted · distorted | Fender Jazz Bass or Rickenbacker 4003 (used by Chris Wolstenholme during that era) | Likely split across multiple amps: clean path (e.g., Ampeg SVT), distorted path (e.g., Marshall live, possibly Orange studio) | 7.5 |
| Madness · solo | Solo · distorted | Manson MB-1 | Diezel VH4 (studio recording, likely channel 3 or 4) | 7 |
| Map of the Problematique · riff | Riff · distorted | Manson MB-1 | Diezel VH4 | 7.5 |
| Micro Cuts · riff | Riff · distorted | Manson MB-1 | Marshall DSL100 | 8.5 |
| MK Ultra · solo | Solo · distorted | Manson MB-1 | Marshall DSL100 | 7.5 |
| Muscle Museum · riff | Riff · distorted | Manson MB-1 (Matt Bellamy signature, early prototype or Manson custom, as used on Showbiz era) | Marshall DSL100 (JCM2000 series, typical for Showbiz era studio recordings) | 7.5 |
| Nightshift Superstar · distorted | Distorted · distorted | Manson Custom 4-string (Chris Wolstenholme signature, active electronics, likely with onboard fuzz circuit) | Fractal Axe-Fx III (amp modeling, likely Ampeg SVT or similar model for distorted section) | 7 |
| Please Please Please Let Me Get What I Want · riff | Riff · distorted | Manson MB-1 | Diezel VH4 | 4.5 |
| Plug In Baby · clean | Clean · clean | Unknown | Unknown | 0 |
| Plug In Baby · riff | Riff · clean | Manson MB-1 | Marshall DSL100 (Dual Super Lead 100W head) | 0 |
| Plug In Baby · solo | Solo · distorted | Manson MB-1 (custom Matt Bellamy signature, built-in Fuzz Factory, MIDI controller) | Diezel VH4 (studio, Channel 3), possibly Marshall JCM2000 (secondary source), but Diezel VH4 is most cited for studio recording | 7.5 |
| Plug In Baby · distorted | Distorted · distorted | Status Graphite S2-Classic (headless, graphite neck, active electronics) | Trace Elliot AH600SMX (studio era), likely with Trace Elliot 4x10 and 1x15 cabs | 7 |
| Plug In Baby (XX Anniversary RemiXX) · riff | Riff · distorted | Manson MB-1 | Marshall JCM 2000 DSL 100 | 8.5 |
| Pressure · riff | Riff · distorted | 1967 Gibson ES-335 with Bigsby (Cherry Red) | Modified Ampeg V-4B (bass amp, modded for more gain) | 7.5 |
| Reapers · solo | Solo · distorted | Manson DL-1 Signature Electric Guitar | Marshall 1959HW Handwired Plexi Head | 8.5 |
| Resistance · solo | Solo · distorted | Manson DL-1 Signature Electric Guitar | Marshall 1959HW Handwired Plexi Head | 7.5 |
| Showbiz · distorted | Distorted · distorted | Pedulla Rapture | Marshall DBS 7400 | 7 |
| Showbiz · clean | Clean · clean | Pedulla Rapture | Marshall DBS 7400 | 0 |
| Showbiz · riff | Riff · distorted | Manson MB-1 (early prototype, Showbiz era, custom built for Matt Bellamy) | Marshall JCM2000 DSL100 | 7.5 |
| Sing for Absolution · riff | Riff · distorted | Gibson SG Standard (red, stock pickups) | Diezel VH4 | 7 |
| Sober · riff | Riff · distorted | Yamaha Pacifica 120 | Line 6 POD 2.0 (direct input, amp model unknown, likely Marshall simulation) | 7.5 |
| Starlight · riff | Riff · clean | Manson MB-1 | Diezel VH4 | 0 |
| Starlight · riff | Riff · distorted | Manson MB-1 (Matt Bellamy signature, custom built by Hugh Manson) | Diezel VH4 | 7 |
| Stockholm Syndrome · solo | Solo · distorted | Manson MB-1 | Diezel VH4 | 8.5 |
| Sunburn · solo | Solo · distorted | Yamaha Pacifica 120S (modified with DiMarzio pickups, Roland GK2 pickup) | Marshall JCM2000 DSL100 | 7.5 |
| Supermassive Black Hole · distorted | Distorted · distorted | Status (likely Status Stealth 5‑string or Signature Status bass used during Black Holes & Revelations era) | Ampeg SVT‑VR (studio) / multiple amps via split signal (clean + Big Muff + Animato) | 7.5 |
| Supermassive Black Hole · solo | Solo · distorted | Manson MB-1 (custom, likely with built-in Fuzz Factory circuit for studio, but Ampeg Dan Armstrong Plexi Electric Guitar seen in music video) | Diezel VH4 (studio, likely channel 3 or 4 for high gain), possible Vox AC30 blended for additional character | 8 |
| Supremacy · solo | Solo · distorted | Manson MB-1 | Marshall 1959HW Plexi Head | 8 |
| Supremacy · clean | Clean · clean | Fender Jazz Bass | Ampeg SVT Classic (likely VR or CL model) | 0 |
| Supremacy · riff | Riff · distorted | Manson MB-1 | Diezel VH4 | 8 |
| The Dark Forest · solo | Solo · distorted | Manson MB-1 | Diezel VH4 | 7.5 |
| The Dark Side · solo | Solo · distorted | Manson MB-1 | Diezel VH4 (studio recording, likely channel 3 or 4 for high gain), possibly blended with Marshall JCM800 (modded by Matt Wells) | 8 |
| The Dark Side · riff | Riff · distorted | Manson MB-1 | Marshall (model not specified, likely JCM800 or similar, as referenced for album sessions) | 7.5 |
| The Handler · riff | Riff · distorted | Manson MB-1 | Diezel VH4 | 8 |
| The Sickness In You & I · riff | Riff · distorted | Manson Delorean (custom, built by Hugh Manson for Matt Bellamy) | Unknown (likely high-gain British-style amp, possibly Diezel or Marshall, but no explicit source for this song/recording) | 8.5 |
| Unintended · riff | Riff · clean | Manson MB-1 (Matt Black) electric guitar | Unknown exact model (likely Marshall or Fender combo, as used by Bellamy in Showbiz era) | 2.5 |
| Unnatural Selection · riff | Riff · distorted | Manson DL-OR (Matt Bellamy signature, custom built by Hugh Manson) | Diezel VH4 (studio recording amp, as used by Bellamy on The Resistance era) | 7 |
| Unravelling · riff | Riff · distorted | Manson Oryx 8-string (custom for Matt Bellamy) | Fractal Axe-Fx III (modeling multiple amps, likely including Marshall, Diezel, Orange, Vox) | 7.5 |
| Uprising · riff | Riff · distorted | Manson MB-1 Signature Electric Guitar | Diezel VH4 100W Tube Guitar Head | 7 |
| Uprising · riff | Riff · clean | Manson MB-1 | Diezel VH4 | 0 |
| Uprising · solo | Solo · distorted | Gibson Les Paul Goldtop (mini humbucker model) | Soldano Decatone 100-Watt Triple Channel Amp Head | 7.5 |
| Won’t Stand Down · riff | Riff · distorted | Manson MB-1 | Diezel VH4 (likely, based on era and typical Muse studio use) | 8.5 |
| Yes Please · riff | Riff · distorted | Manson MB-1 (custom, early 2000s version) | Marshall JCM2000 DSL 100 (studio recording, 2001) | 8.5 |